. Form liquid
\n. Alternative Name ABC29; ABCC; ABCC1; ATP-binding cassette sub-family C member 1; ATP-binding cassette, sub-family C(CFTR\/MRP), member 1; EC 3.6.3; EC 3.6.3.44; GS-X; Leukotriene C(4) transporter; LTC4 transporter; MRP1;multidrug resistance associated protein 1; multidrug resistance protein; multidrug resistance-associated protein 1; multiple drug resistance protein 1; multiple drug resistance-associated protein
\n. Purification Immunogen affinity purified
\n. Purity 95% as determined by SDS-PAGE
\n. Host Rabbit
\n. Isotype IgG
\n. Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze \/ thaw cycles.)
\n. Background\/ FUNCTION
\n. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.
\n. Immunogen ABCC1
\n. Specificity Human, Mouse, Rat
\n. Tested Application ELISA, IHC, WB
\n. Recommended dilution WB 1:500-1:1000; IHC 1:50-1:100
\n. IHC use Immunohistochemistry of paraffin-embedded Human lung cancer tissue using PAab09806(ABCC1 antibody) at dilution of 1:50
\n. WB use
\n. A549 cell lysate were subjected to SDS PAGE followed by western blot with PAab09806(ABCC1 antibody) at dilution of 1:500
\n. Protein Information
\n. Gene ID
\n. Uniprot ID P33527
\n. Calculated MW
\n. Research Area <\/p>\n","protected":false},"excerpt":{"rendered":"
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