{"id":27522,"date":"2023-08-16T19:11:58","date_gmt":"2023-08-16T17:11:58","guid":{"rendered":"https:\/\/biocore-diagnostics.de\/?post_type=product&#038;p=27522"},"modified":"2023-08-24T19:20:37","modified_gmt":"2023-08-24T17:20:37","slug":"alpha-synuclein-antibody","status":"publish","type":"product","link":"https:\/\/biocore-diagnostics.de\/de\/produkt\/alpha-synuclein-antibody\/","title":{"rendered":"ALPHA-SYNUCLEIN ANTIBODY"},"content":{"rendered":"<p>. Form liquid<br \/>\n. Alternative Name Alpha synuclein, NACP, PARK1, PARK4, SNCA<br \/>\n. Purification protein A+G purified<br \/>\n. Purity 95% as determined by SDS-PAGE<br \/>\n. Host Mouse<br \/>\n. Isotype IgG1<br \/>\n. Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze \/ thaw cycles.)<br \/>\n. Background\/ FUNCTION<br \/>\n. Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer&#8217;s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.<br \/>\n. Immunogen synuclein, alpha (non A4 component of amyloid precursor)<br \/>\n. Specificity Human, Mouse, Rat<br \/>\n. Tested Application ELISA, IHC, WB<br \/>\n. Recommended dilution WB: 1:500 &#8211; 1:2000; IHC: 1:500 &#8211; 1:2000<br \/>\n. IHC use Immunohistochemistry of paraffin-embedded mouse brain using PAab09891(SNCA antibody) at dilution of 1:1000<br \/>\n. WB use<br \/>\n. mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab09891(SNCA antibody) at dilution of 1:1000<br \/>\n. Protein Information<br \/>\n. Gene ID 6622<br \/>\n. Uniprot ID P37840<br \/>\n. Calculated MW 23 kDa<br \/>\n. Research Area Neuroscience<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Packing 100ul<\/p>\n","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[15,418,419],"product_tag":[],"class_list":{"0":"post-27522","1":"product","2":"type-product","3":"status-publish","5":"product_cat-all","6":"product_cat-lifescience-markt","7":"product_cat-plasmid","10":"instock","11":"taxable","12":"shipping-taxable","13":"product-type-simple","14":"product-grid-view"},"acf":[],"_links":{"self":[{"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/product\/27522","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/comments?post=27522"}],"wp:attachment":[{"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/media?parent=27522"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/product_brand?post=27522"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/product_cat?post=27522"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/product_tag?post=27522"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}