{"id":27534,"date":"2023-08-18T20:18:06","date_gmt":"2023-08-18T18:18:06","guid":{"rendered":"https:\/\/biocore-diagnostics.de\/?post_type=product&#038;p=27534"},"modified":"2023-08-23T20:41:18","modified_gmt":"2023-08-23T18:41:18","slug":"arhgef1-antibody","status":"publish","type":"product","link":"https:\/\/biocore-diagnostics.de\/de\/produkt\/arhgef1-antibody\/","title":{"rendered":"ARHGEF1 ANTIBODY"},"content":{"rendered":"<p>. Form liquid<br \/>\n. Alternative Name ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5, ARHG1<br \/>\n. Purification Immunogen affinity purified<br \/>\n. Purity 95% as determined by SDS-PAGE<br \/>\n. Host Rabbit<br \/>\n. Isotype IgG<br \/>\n. Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze \/ thaw cycles.)<br \/>\n. Background\/ FUNCTION<br \/>\n. Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13\/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.<br \/>\n. Immunogen Rho guanine nucleotide exchange factor(GEF) 1<br \/>\n. Specificity Human, Rat<br \/>\n. Tested Application ELISA, IHC<br \/>\n. Recommended dilution IHC: 1:20-1:200<br \/>\n. IHC use Immunohistochemistry of paraffin-embedded rat lung using PAab10091(PER2 antibody) at dilution of 1:50<br \/>\n. WB use<br \/>\n. Protein Information<br \/>\n. Gene ID 9138<br \/>\n. Uniprot ID Q92888<br \/>\n. Calculated MW 102-110 kDa<br \/>\n. Research Area Signal Transduction, Metabolism<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Packing 100ul<\/p>\n","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[15,418,419],"product_tag":[],"class_list":{"0":"post-27534","1":"product","2":"type-product","3":"status-publish","5":"product_cat-all","6":"product_cat-lifescience-markt","7":"product_cat-plasmid","10":"instock","11":"taxable","12":"shipping-taxable","13":"product-type-simple","14":"product-grid-view"},"acf":[],"_links":{"self":[{"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/product\/27534","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/comments?post=27534"}],"wp:attachment":[{"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/media?parent=27534"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/product_brand?post=27534"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/product_cat?post=27534"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/biocore-diagnostics.de\/de\/wp-json\/wp\/v2\/product_tag?post=27534"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}