ANA-8S is a solid phase enzyme immunoassay for the combined qualitative detection of IgG antibodies against eight cellular and nuclear antigens in human serum. Each well is coated with recombinant 70 kDa U1-snRNP, SS-B, SS-A 52 kDa, Scl 70, centromere protein B (CenpB), Jo-1 and highly purified native human snRNP/Sm, Sm and SS-A 60 kDa. The assay is a tool in the differential diagnosis of systemic rheumatic diseases
ANA-8Pro is a solid phase enzyme immunoassay for the separate qualitative detection of IgG antibodies against eight cellular and nuclear antigens in human serum. The wells are separately coated with recombinant 70 kDa U1 snRNP, SS-B, SS-A 52 kDa, Scl 70, centromere protein B (CenpB), Jo-1 and highly purified native human snRNP/Sm, Sm and SS-A 60 kDa. The assay is a tool in the differential diagnosis of systemic rheumatic diseases.
ENA-6S is a solid phase enzyme immunoassay for the combined qualitative detection of IgG antibodies against six cellular and nuclear antigens in human serum. Each well is coated with recombinant SS-B, SS-A 52 kDa, Scl 70, Jo-1 and highly purified native human snRNP/Sm, Sm and SS-A 60 kDa. The assay is a tool in the differential diagnosis of systemic rheumatic diseases
ENA-6Pro is a solid phase enzyme immunoassay for the separate semi-quantitative detection of IgG antibodies against six cellular and nuclear antigens in human serum. The wells are coated with recombinant SS-B, SS-A 52 kDa, Scl 70, Jo-1 and highly purified native human snRNP/Sm, Sm and SS-A 60 kDa. The assay is a tool in the differential diagnosis of systemic rheumatic diseases.
U1-70 is a solid phase enzyme immunoassay employing recombinant human 70 kDa protein of the U1-snRNP complex for the quantitative detection of antibodies against the 70 kDa U1-RNP in human serum. The assay is a tool in the diagnosis of mixed connective tissue diseases (MCTD) and systemic lupus erythematosus (SLE).
snRNP-C is a solid phase enzyme immunoassay for the quantitative detection of antibodies against the snRNP complex in human serum. The assay employs native human U1-snRNP complex highly purified from the cell-line HeLa. The U1-snRNP complex comprises the Smith antigen (Sm) and RNPs, the 70kDa U1-specific protein plus protein A and C. The assay is a tool for the diagnosis of mixed connective tissue diseases (MCTD) and systemic lupus erythematosus (SLE)
Sm is a solid phase enzyme immunoassay with highly purified native Smith antigen (Sm) from human eukaryotic cells (HeLa) for the quantitative detection of antibodies against Sm in human serum. Anti-Sm antibodies recognize specific conformational epitopes only accessible on native human Sm. The assay is a tool in the differential diagnosis of systemic lupus erythematosus (SLE).
SS-A is a solid phase enzyme immunoassay for the quantitative detection of antibodies against Ro/ SS-A in human serum. The assay employs human Ro/SS-A antigen composed of highly purified native 60kDa and recombinant human 52 kDa Ro/SS-A protein. Anti-SS-A antibodies are species-specific (directed against human protein only) and preferentially react with the native 60kDa molecule where as most antibodies to the 52 kDa protein prefer the denatured molecule. The assay is a tool in the diagnosis of Sjögren`s syndrome (SS) and systemic lupus erythematosus (SLE).
SS-B is a solid phase enzyme immunoassay employing human recombinant La-antigen/ SS-B for the quantitative detection of antibodies against La-antigen / SS-B in human serum. The assay is a tool in the diagnosis of Sjögren`s syndrome (SS) and systemic lupus erythematosus (SLE).
Scl-70 is a solid phase enzyme immunoassay with human recombinant 70 kDa fragment of DNA topoisomerase I for the quantitative detection of antibodies against Scl-70 (70 kDa scleroderma antigen) in human serum. The assay is a tool in the differential diagnosis of systemic sclerosis.
Cenp-B is a solid phase enzyme immunoassay employing purified recombinant human 80 kDa centromere protein B (Cenp-B) for the quantitative and qualitative detection of IgG antibodies against Cenp-B in human serum. The assay ensures the highest specificity and sensitivity for the detection of antibodies against centromere protein B, which serves as an aid in the diagnosis of systemic sclerosis and CREST syndrome.
Jo-1 is a solid phase enzyme immunoassay with recombinant human histidyl-tRNA-synthetase (HRS) for the quantitative detection of antibodies against Jo-1 (named after the prototype patient) in human serum. Human sera with anti-Jo-1 antibodies solely recognize HRS of higher eukaryotes and react with highest affinity with the human enzyme. The assay is a tool in the diagnosis of polymyositis and dermatomyositis.
Rib-P is a solid phase enzyme immunoassay employing native human ribosomal P-proteins P0, P1 and P2 isolated from eukaryotic cell line for the quantitative detection of antibodies against ribosomal P-proteins (rib-P) in human serum. The specificity of anti-rib-P antibodies is restricted to a common antigenic determinant located on the highly conserved carboxyl-terminal portion of the three P proteins. The assay is a tool in the diagnosis of systemic lupus erythematosus (SLE).
ANA-HEp-2 is a solid phase enzyme immunoassay for the combined qualitative detection of IgG antibodies against HEp2 cells in human serum. Each well is coated with lysed HEp2 cells. The test collectively detects, in one well, total ANAs against double stranded DNA (dsDNA), histones, SS-A (Ro), SS-B (La), Sm, snRNP/Sm, Scl-70, PM-Scl, Jo-1 and centromeric antigens along with sera positive for HEp2 immunofluorescence test (IFT). The assay is a tool in the diagnosis of systemic rheumatic diseases like systemic lupus erythematosus (SLE), mixed connective tissue diseases (MCTD), scleroderma, Sjögren`s syndrome, polymyositis and dermatomyositis.
DANA-Pro is a solid phase enzyme immunoassay for the separate qualitative detection of IgG antibodies against eight cellular and nuclear antigens in human serum. The wells are separately coated with recombinant dsDNA, 70 kDa U1 snRNP, SS-B, SS-A 52 kDa, Scl 70, centromere protein B (CenpB), Jo-1 and highly purified native human Sm and SS-A 60 kDa. The assay is a tool in the differential diagnosis of systemic rheumatic diseases.
Sclero-Pro is a solid phase enzyme immunoassay for the separate qualitative detection of IgG antibodies against eight different cellular and nuclear antigens in human serum. The wells are separately coated with recombinant human 100 kDa PM-Scl, 70 kDa U1-snRNP, SS-B, SS-A 52 kDa, SS-A 60 kDa, Scl 70, centromere protein B (CenpB), Jo-1 and highly purified native human Sm. The assay is a tool in the differential diagnosis of systemic rheumatic diseases.
Nucleo-h is a solid phase enzyme immunoassay with human native nucleosomes isolated from the eukaryotic celline HeLa for the quantitative detection of antibodies against nucleosomes and their components dsDNA and histones in human serum. The assay is a tool in the differential diagnosis of systemic lupus erythematosus (SLE).
dsDNA-Check is a solid phase enzyme immunoassay with human recombinant double-stranded DNA (dsDNA) for the combined quantitative detection of IgG, IgA and IgM antibodies against dsDNA in human serum.The assay is a tool in the differential diagnosis of systemic lupus erythematosus (SLE).
dsDNA-G is a solid phase enzyme immunoassay with human recombinant double-stranded DNA (dsDNA) for the quantitative detection of IgG antibodies against dsDNA in human serum. The assay is a tool in the differential diagnosis of systemic lupus erythematosus (SLE).
ssDNA-Check is a solid phase enzyme immunoassay with human recombinant single-stranded DNA (ssDNA) for the quantitative detection of IgA/G/M antibodies against ssDNA in human serum. Antibodies against ssDNA mainly recognize its basic compound, which is masked inside the helical structure of native DNA. The assay is a tool in the differential diagnosis of systemic lupus erythematosus (SLE).
ssDNA-A is a solid phase enzyme immunoassay with human recombinant single-stranded DNA (ssDNA) for the quantitative detection of IgA antibodies against ssDNA in human serum. Antibodies against ssDNA mainly recognize its basic compound, which is masked inside the helical structure of native DNA. The assay is a tool in the differential diagnosis of systemic lupus erythematosus (SLE).
ssDNA-G is a solid phase enzyme immunoassay with human recombinant single-stranded DNA (ssDNA) for the quantitative detection of IgG antibodies against ssDNA in human serum. Antibodies against ssDNA mainly recognize its basic compound, which is masked inside the helical structure of native DNA. The assay is a tool in the differential diagnosis of systemic lupus erythematosus (SLE).
ssDNA-M is a solid phase enzyme immunoassay with human recombinant single-stranded DNA (ssDNA) for the quantitative detection of IgM antibodies against ssDNA in human serum. Antibodies against ssDNA mainly recognize its basic compound, which is masked inside the helical structure of native DNA. The assay is a tool in the differential diagnosis of systemic lupus erythematosus (SLE).
Histone-C is a solid phase enzyme immunoassay with human native histones H1, H2A, H2B, H3, H4 isolated from the eukaryotic celline HeLa for the quantitative detection of antibodies against histones in human serum. The assay is a tool in the differential diagnosis of systemic lupus erythematosus (SLE).
Rf-Check is a solid phase enzyme immunoassay with highly purified Fc fragment of human immunoglobuline (IgG) for the combined quantitative detection of IgG, IgM and IgA rheumatoid factors (RF) in human serum. The assay is an aid in the diagnosis of rheumatoid arthritis (RA).
Rf-AGM is a solid phase enzyme immunoassay with highly purified Fc fragment of human immunoglobuline (IgG) for the separate quantitative detection of IgG, IgM and IgA rheumatoid factors (RF) in human serum. The assay is an aid in the diagnosis of rheumatoid arthritis (RA).
RA/CP Detect is a solid phase enzyme immunoassay for the quantitative detection of IgG antibodies to specific synthetic citrullinated peptides of human immunoglobulin G (IgG) in human serum. The assay is an aid in the diagnosis of rheumatoid arthritis (RA).
CCP is a solid phase enzyme immunoassay for the quantitative detection of IgG antibodies to specific cyclic citrullinated peptides. The assay is an aid in the diagnosis of rheumatoid arthritis (RA).