Description

. Form liquid
. Alternative Name ARF GAP 1, ARF1 GAP, ARF1GAP, ARFGAP1, HRIHFB2281
. Purification Immunogen affinity purified
. Purity 95% as determined by SDS-PAGE
. Host Rabbit
. Isotype IgG
. Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
. Background/ FUNCTION
. The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.
. Immunogen ADP-ribosylation factor GTPase activating protein 1
. Specificity Human, Rat
. Tested Application ELISA, WB
. Recommended dilution WB: 1:500 – 1:2000
. IHC use
. WB use
. Hela cells were subjected to SDS PAGE followed by western blot with PAab10028(ARFGAP1 antibody) at dilution of 1:1000
. Protein Information
. Gene ID 55738
. Uniprot ID Q8N6T3
. Calculated MW 45 kDa
. Research Area Signal Transduction