Biocore offers a broad range of tumor diagnostic tests for the early detection and monitoring of patients undergoing treatment. biocore offers screening tests as well as quantitative tests that are particularly suitable for the detection and monitoring of minimal residual disease (MRD). MRD is the small number of leukemic or solid tumor cells that remain in the patient during or after treatment when the patient is in remission (no symptoms or signs of disease). It is the major cause of relapse in cancer and leukemia. Particularly unique are the highly multiplexed real-time PCR tests for the simultaneous detection of up to 30 different translocations in acute and chronic leukemia with only one test (HemaVision®, Q-Fusion). In addition to leukemia, molecular markers of various carcinomas and sarcomas can also be used. In addition to MRD tests, the division offers a range of somatic mutation tests that are important in the management of various cancers.
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DC-10-2010
QClamp® KRAS Codon Specific Mutation Test in Codons 12, 13, 59, 61, 117 & 146
10
The QClamp® KRAS Codon Specific Mutation Test in Codons 12, 13, 59, 61, 117, & 146 is a real-time qualitative PCR assay for the detection of somatic mutations in and near Codons 12 and 13 in Exon 2, Codons 59 and 61 in Exon 3, and Codons 117 and 146 in Exon 4 in the human KRAS gene, using purified DNA extracted from FFPE (formalin fixed paraffin embedded), cells or tissue.
QClamp® NRAS Codon Specific Mutation Test in Codons 12, 13, 59, 61, 117 & 146
10
The QClamp® NRAS Codon Specific Mutation Test in Codons 12, 13, 59, 61, 117, & 146 is a real-time qualitative PCR assay for the detection of somatic mutations in and near NRAS Codon 12 and 13 in Exon 2, Codon 59 and 61 in Exon 3, and Codon 146 in Exon 4 in the human NRAS gene, using purified DNA extracted from FFPE (formalin fixed paraffin embedded), cells or tissue.
QClamp® EGFR Codon Specific Mutation in Codons 719, Ex19Del, 790, 858 & 861
10
The QClamp® EGFR Codon Specific Mutation Test in Codons Ex19 Del, Codons 719, 790, 858, & 861 is a real-time PCR assay for the detection of somatic mutations in and near EGFR codon 719 in Exon 18, Exon 19 deletions, codon 790 in Exon 20 and codon 858 and codon 861 in Exon 21, in the human EGFR (epidermal growth factor receptor) gene, using purified DNA extracted from FFPE (formalin fixed paraffin embedded), cells or tissue.
QClamp® BRAF Codon Specific Mutation Test in Codon 600
10
The QClamp® BRAF Codon Specific Mutation Test in Codon 600 is a real-time PCR assay for the detection of somatic mutations in and near codon 600 in exon 15, in the BRAF serine/threonine protein kinase gene, using purified DNA extracted from FFPE (formalin fixed paraffin embedded), cells or tissue.
QClamp® JAK2 Codon Specific Mutation Test in Codon 617
10
The QClamp® JAK2 Codon Specific Mutation Test in Codon 617 is a real-time PCR assay for the detection of somatic mutations in and near JAK2 codon 617 in Exon 14 in the JAK2 tyrosine kinase gene, using purified DNA extracted from FFPE (formalin fixed paraffin embedded), cells or tissue.
The QClamp® PIK3CA Codon Specific Mutation Test in Codons 542, 545, & 1047 is a real-time qualitative PCR assay for the detection of somatic mutations in the human PIK3CA gene, using genomic DNA extracted from cells or FFPE (formalin fixed paraffin embedded) cells or tissue. Detects: 542, 545 and 1047. Sample type: FFPE or plasma
ColoScape™ Colorectal Cancer Mutation Detection Kit
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Kit for qualitative detection of colorectal cancer associated mutations including APC (codons 1309, 1367, 1450), KRAS (codons 12 and 13), BRAF (codon 600) and CTNNB1 (codons 41 and 45) from blood
