Description
Vasculitis-Screen is a solid phase enzyme immunoassay for the combined quantitative detection of antibodies against PR3 and MPO in human serum. Each well is coated with native human proteinase 3 (PR3) plus native myeloperoxidase (MPO), both highly purified from human peripheral blood polymorphnuclear cells. Anti-PR3 and anti-MPO antibodies recognize specificially conformational epitopes only accessible on the native target antigen. The assay is an aid in the differential diagnosis of autoimmune vasculitis.