Description

. Form liquid
. Alternative Name ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3
. Purification Immunogen affinity purified
. Purity 95% as determined by SDS-PAGE
. Host Rabbit
. Isotype IgG
. Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
. Background/ FUNCTION
. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
. Immunogen Tyrosinase
. Specificity Human, Mouse, Rat
. Tested Application ELISA, WB, IHC, IF
. Recommended dilution WB: 1:500 – 1:2000; IHC: 1:50 – 1:200; IF: 1:50 – 1:200
. IHC use Immunohistochemistry of paraffin-embedded rat heart using PAab09856(TYR antibody) at dilution of 1:100
. WB use
. mouse liver were subjected to SDS PAGE followed by western blot with PAab09856(TYR antibody) at dilution of 1:1000
. Protein Information
. Gene ID 7299
. Uniprot ID P14679
. Calculated MW 126 kDa
. Research Area Signal Transduction, Metabolism, Cancer