Description

. Form liquid
. Alternative Name TBC1D4, AS160, NIDDM5, TBC1 domain family member 4, TBC (Tre-2, BUB2, CDC16) domain-containing protein, akt substrate of 160 kDa
. Purification Immunogen affinity purified
. Purity 95% as determined by SDS-PAGE
. Host Rabbit
. Isotype IgG
. Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
. Background/ FUNCTION
. May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake.
. Immunogen AS160
. Specificity Human, Mouse, Rat
. Tested Application ELISA, WB
. Recommended dilution WB: 1:500 – 1:2000
. IHC use
. WB use
. RAW 264.7 were subjected to SDS PAGE followed by western blot with PAab09889(AS160 antibody) at dilution of 1:1000
. Protein Information
. Gene ID
. Uniprot ID O60343
. Calculated MW 50-55 kDa
. Research Area Signal Transduction