Products

. Form liquid . Alternative Name 4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma. . Immunogen eukaryotic translation initiation factor 4E binding protein 1 . Specificity Human, Mouse, Rat . Tested Application ELISA, WB, IHC, IF . Recommended dilution WB: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:200 . IHC use Immunohistochemistry of paraffin-embedded human breast cancer slide using PAab10129(4EBP1 Antibody) at dilution of 1:50 . WB use . MCF7 cells were subjected to SDS PAGE followed by western blot with PAab10129(4EBP1 antibody) at dilution of 1:1000 . Protein Information . Gene ID 1978 . Uniprot ID Q13541 . Calculated MW 17 kDa . Research Area Cancer, Metabolism

. Form liquid . Alternative Name . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Immunogen 5-hydroxytryptamine . Specificity . Tested Application ELISA, IHC . Recommended dilution IHC: 1:50-1:500 . IHC use Immunohistochemistry of paraffin-embedded rat brain tissue slide using PAab09928 (5-HT antibody) at dilution of 1:200 . WB use . Protein Information . Gene ID . Uniprot ID . Calculated MW . Research Area

. Form liquid . Alternative Name APOBEC3A, A3A, ARP3, PHRBN, bK150C2.1, DNA dC->dU-editing enzyme APOBEC-3A . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Immunogen APOBEC-3A . Specificity Human, Rat . Tested Application ELISA, WB, IHC . Recommended dilution WB: 1:200-1:2000; IHC: 1:50-1:500 . IHC use Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using PAab10020(ABC3A Antibody) at dilution of 1:200 . WB use . rat testis were subjected to SDS PAGE followed by western blot with PAab10020( ABC3A Antibody) at dilution of 1:1000 . Protein Information . Gene ID 200315 . Uniprot ID P31941 . Calculated MW 26 kDa . Research Area Signal Transduction, Metabolism

. Form liquid . Alternative Name ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1 . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. . Immunogen ABCA4 . Specificity Human . Tested Application ELISA, IHC . Recommended dilution IHC: 1:20-1:200 . IHC use Immunohistochemistry of paraffin-embedded human colon cancer using PAab10057(ABCA4 antibody) at dilution of 1:100 . WB use . Protein Information . Gene ID 24 . Uniprot ID P78363 . Calculated MW 256 kDa . Research Area Signal Transduction

. Form liquid . Alternative Name ABC29; ABCC; ABCC1; ATP-binding cassette sub-family C member 1; ATP-binding cassette, sub-family C(CFTR/MRP), member 1; EC 3.6.3; EC 3.6.3.44; GS-X; Leukotriene C(4) transporter; LTC4 transporter; MRP1;multidrug resistance associated protein 1; multidrug resistance protein; multidrug resistance-associated protein 1; multiple drug resistance protein 1; multiple drug resistance-associated protein . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . The protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. . Immunogen ABCC1 . Specificity Human, Mouse, Rat . Tested Application ELISA, IHC, WB . Recommended dilution WB 1:500-1:1000; IHC 1:50-1:100 . IHC use Immunohistochemistry of paraffin-embedded Human lung cancer tissue using PAab09806(ABCC1 antibody) at dilution of 1:50 . WB use . A549 cell lysate were subjected to SDS PAGE followed by western blot with PAab09806(ABCC1 antibody) at dilution of 1:500 . Protein Information . Gene ID . Uniprot ID P33527 . Calculated MW . Research Area

. Form liquid . Alternative Name Actinin, alpha 3, ACTN3, Alpha actinin 3, F actin cross linking protein . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. . Immunogen actinin, alpha 3 . Specificity Rat . Tested Application ELISA, WB, IHC . Recommended dilution WB: 1:500-1:2000; IHC: 1:50-1:500 . IHC use Immunohistochemistry of paraffin-embedded rat heart tissue slide using PAab10008(ACTN3 Antibody) at dilution of 1:200 . WB use . rat skeletal muscle tissue were subjected to SDS PAGE followed by western blot with PAab10008(ACTN3 Antibody) at dilution of 1:1000 . Protein Information . Gene ID 89 . Uniprot ID Q08043 . Calculated MW 103 kDa . Research Area Immunology

. Form liquid . Alternative Name ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28 . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. . Immunogen ADIPOQ . Specificity Human, Mouse, Rat . Tested Application ELISA, WB, IHC . Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 . IHC use Immunohistochemistry of paraffin-embedded mouse kidney using PAab09814(ADIPOQ Antibody) at dilution of 1:100 . WB use . Jurkat cells were subjected to SDS PAGE followed by western blot with PAab09814 at dilution of 1:1000 . Protein Information . Gene ID 9370 . Uniprot ID Q15848 . Calculated MW 33 kDa . Research Area

. Form liquid . Alternative Name AGER, RAGE . Purification protein A+G purified . Purity 95% as determined by SDS-PAGE . Host Mouse . Isotype IgG1 . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Mediates interactions of advanced glycosylation end products(AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling(By similarity). Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide(ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase(MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides. . Immunogen advanced glycosylation end product-specific receptor . Specificity Human, Rat . Tested Application ELISA, WB . Recommended dilution WB: 1:1000-1:5000 . IHC use . WB use . Rar lung tissue were subjected to SDS PAGE followed by western blot with PAab09951(AGER Antibody) at dilution of 1:2000 . Protein Information . Gene ID 177 . Uniprot ID Q15109 . Calculated MW 43 kDa . Research Area Immunology, Signal Transduction, Developmental biology

. Form liquid . Alternative Name A2HS, AHS, FETUA, HSGA . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. . Immunogen alpha-2-HS-glycoprotein . Specificity Human . Tested Application ELISA, WB, IF . Recommended dilution WB: 1:500 - 1:2000; IF: 1:50 - 1:200 . IHC use . WB use . 293T cells were subjected to SDS PAGE followed by western blot with PAab09916(AHSG Antibody) at dilution of 1:1000 . Protein Information . Gene ID 197 . Uniprot ID P02765 . Calculated MW 68 kDa . Research Area Cardiovascular, Metabolism, Developmental biology, Signal Transduction, Neuroscience, Immunology

. Form liquid . Alternative Name AIF 1, AIF1, G1, IBA1, IRT 1, Protein G1 . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . AIF1, also named as G1, IBA1 or daintain/AIF-1, is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage. Despite a lack of detailed knowledge on the in vivo physiological functions of AIF-1, there is growing evidence that shows its aberrant expression contributes to the pathogenesis of many autoimmune diseases, including rheumatoid arthritis. (20944424). AIF1 is an actin-binding protein that enhances membrane ruffling and RAC activation. It enhances lymphocyte migration and the actin-bundling activity of LCP1. AIF1 plays a role in RAC signaling and in phagocytosis and a role in vascular inflammation. AIF1 promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. It is also as a microglial cell marker. . Immunogen allograft inflammatory factor 1 . Specificity Human, Mouse, Rat . Tested Application ELISA, WB . Recommended dilution WB: 1:500-1:2000 . IHC use . WB use . U937 cells were subjected to SDS PAGE followed by western blot with PAab09944(AIF1 antibody) at dilution of 1:1000 . Protein Information . Gene ID 199 . Uniprot ID P55008 . Calculated MW 16 kDa . Research Area Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Neuroscience, Stem Cells, Immunology

. Form liquid . Alternative Name Alpha synuclein, NACP, PARK1, PARK4, SNCA . Purification protein A+G purified . Purity 95% as determined by SDS-PAGE . Host Mouse . Isotype IgG1 . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. . Immunogen synuclein, alpha (non A4 component of amyloid precursor) . Specificity Human, Mouse, Rat . Tested Application ELISA, IHC, WB . Recommended dilution WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000 . IHC use Immunohistochemistry of paraffin-embedded mouse brain using PAab09891(SNCA antibody) at dilution of 1:1000 . WB use . mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab09891(SNCA antibody) at dilution of 1:1000 . Protein Information . Gene ID 6622 . Uniprot ID P37840 . Calculated MW 23 kDa . Research Area Neuroscience

. Form liquid . Alternative Name AMH, anti Mullerian hormone, MIF, MIS . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Immunogen anti-Mullerian hormone . Specificity Human . Tested Application ELISA, IHC,IF . Recommended dilution IHC: 1:20-1:200; IF: 1:20-1:200 . IHC use Immunohistochemistry of paraffin-embedded human ovary tissue slide using PAab09798(AMH Antibody) at dilution of 1:100 . WB use . Protein Information . Gene ID 268 . Uniprot ID P03971 . Calculated MW . Research Area Immunology, Signal Transduction, Developmental biology

. Form liquid . Alternative Name AMOT, angiomotin, KIAA1071 . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Angiomotin belongs to the motin family of angiostatin binding protein. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Most abundant expression was found in placenta and skeletal muscle. AMOT has two isoforms with MW 130 kDa (p130) and 80 kDa (p80). The p130 isoform can interact with F-actin.This antibody recognizes both p130 and p80. . Immunogen angiomotin . Specificity Human . Tested Application ELISA, WB, IHC, IF, IP . Recommended dilution WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200 . IHC use Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using PAab09852(AMOT Antibody) at dilution of 1:200 . WB use . HEK293 cells were subjected to SDS PAGE followed by western blot with PAab09852(AMOT Antibody) at dilution of 1:1000 . Protein Information . Gene ID 154796 . Uniprot ID Q4VCS5 . Calculated MW 62 kDa . Research Area Cardiovascular, Developmental biology

. Form liquid . Alternative Name ANGPTL8, Betatrophin, C19orf80, LOC55908, PRO1185, PVPA599, td26 . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Immunogen Betatrophin . Specificity human, mouse . Tested Application ELISA, WB, IHC . Recommended dilution WB: 1:500-1:2000; IHC: 1:20-1:200 . IHC use Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab09883( ANGPTL8 antibody at dilution of 1:100 . WB use . Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with PAab09883( ANGPTL8 antibody at dilution of 1:1000 . Protein Information . Gene ID 55908 . Uniprot ID Q6UXH0 . Calculated MW 29 kDa . Research Area Cell Division and Proliferation

. Form liquid . Alternative Name Anchorin CII, Annexin 5, annexin A5, Annexin V, ANX5, ANXA5, Calphobindin I, CBP I, Endonexin II, ENX2, Lipocortin V, PAP I, PP4, Thromboplastin inhibitor, VAC alpha, Vascular anticoagulant alpha . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Annexin A5(ANXA5), is a member of the structurally related family of?annexin?proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. . Immunogen annexin A5 . Specificity Human, Mouse . Tested Application ELISA, WB . Recommended dilution WB: 1:200-1:2000 . IHC use . WB use . HeLa cells were subjected to SDS PAGE followed by western blot with PAab09988(ANXA5 antibody) at dilution of 1:1000 . Protein Information . Gene ID 308 . Uniprot ID P08758 . Calculated MW 36 kDa . Research Area Cancer, Cardiovascular, Metabolism, Signal Transduction

. Form liquid . Alternative Name ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. . Immunogen Tyrosinase . Specificity Human, Mouse, Rat . Tested Application ELISA, WB, IHC, IF . Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 . IHC use Immunohistochemistry of paraffin-embedded rat heart using PAab09856(TYR antibody) at dilution of 1:100 . WB use . mouse liver were subjected to SDS PAGE followed by western blot with PAab09856(TYR antibody) at dilution of 1:1000 . Protein Information . Gene ID 7299 . Uniprot ID P14679 . Calculated MW 126 kDa . Research Area Signal Transduction, Metabolism, Cancer

. Form liquid . Alternative Name Adenomatous polyposis coli protein-like, APC-like, APCL . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Immunogen Adenomatous polyposis coli protein 2 . Specificity Human, rat . Tested Application ELISA, IHC . Recommended dilution IHC: 1:20-1:200 . IHC use Immunohistochemistry of paraffin-embedded rat brain tissue using PAab10003(APC2 Antibody) at dilution of 1:200 . WB use . Protein Information . Gene ID . Uniprot ID O95996 . Calculated MW . Research Area Cell Division and Proliferation, Metabolism

. Form liquid . Alternative Name APOE, AD2 APO-E ApoE4 LDLCQ5, LPG, apolipoprotein E . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Immunogen apolipoprotein E 33B . Specificity Human, Mouse, Rat . Tested Application ELISA, WB, IHC, IF . Recommended dilution WB: 1:200-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200 . IHC use Immunohistochemistry of paraffin-embedded human stomach tissue slide using PAab10127 (APOE Antibody) at dilution of 1:100. . WB use . SKOV3 cells were subjected to SDS PAGE followed by western blot with PAab10127 (APOE antibody) at dilution of 1:1000 . Protein Information . Gene ID 348 . Uniprot ID P02649 . Calculated MW 35 kDa . Research Area

. Form liquid . Alternative Name AQP2, AQP-CD, WCH-CD . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Immunogen aquaporin-2 . Specificity Human, Mouse, Rat . Tested Application ELISA, WB, IHC . Recommended dilution WB: 1:500-1:2000; IHC: 1:50-1:200 . IHC use Immunohistochemistry of paraffin-embedded rat kidney tissue slide using PAab09924 (AQP2 antibody) at dilution of 1:100 . WB use . mouse kidney were subjected to SDS PAGE followed by western blot with PAab09924 (AQP2 antibody) at dilution of 1:1000 . Protein Information . Gene ID 359 . Uniprot ID P41181 . Calculated MW 28 kDa . Research Area Metabolism, Signal Transduction

. Form liquid . Alternative Name AQP-9, HsT17287, SSC1, T17287 . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid . repeated freeze / thaw cycles.) . Background/ FUNCTION . The aquaporins are a family of water-selective membrane channels. This gene encodes a member of a subset of aquaporins called the aquaglyceroporins. This protein allows passage of a broad range of noncharged solutes and also stimulates urea transport and osmotic water permeability. This protein may also facilitate the uptake of glycerol in hepatic tissue . The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. Alternate splicing results in multiple transcript variants. . Immunogen Aquaporin-9 . Specificity Human, Mouse, Rat . Tested Application ELISA, WB . Recommended dilution WB: 1:500 - 1:2000 . IHC use . WB use . rat liver were subjected to SDS PAGE followed by western blot with PAab09925 (AQP9 antibody) at dilution of 1:1000 . Protein Information . Gene ID 366 . Uniprot ID O43315 . Calculated MW 38 kDa . Research Area Metabolism, Signal Transduction

. Form liquid . Alternative Name ARF GAP 1, ARF1 GAP, ARF1GAP, ARFGAP1, HRIHFB2281 . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. . Immunogen ADP-ribosylation factor GTPase activating protein 1 . Specificity Human, Rat . Tested Application ELISA, WB . Recommended dilution WB: 1:500 - 1:2000 . IHC use . WB use . Hela cells were subjected to SDS PAGE followed by western blot with PAab10028(ARFGAP1 antibody) at dilution of 1:1000 . Protein Information . Gene ID 55738 . Uniprot ID Q8N6T3 . Calculated MW 45 kDa . Research Area Signal Transduction

. Form liquid . Alternative Name ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5, ARHG1 . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation. . Immunogen Rho guanine nucleotide exchange factor(GEF) 1 . Specificity Human, Rat . Tested Application ELISA, IHC . Recommended dilution IHC: 1:20-1:200 . IHC use Immunohistochemistry of paraffin-embedded rat lung using PAab10091(PER2 antibody) at dilution of 1:50 . WB use . Protein Information . Gene ID 9138 . Uniprot ID Q92888 . Calculated MW 102-110 kDa . Research Area Signal Transduction, Metabolism

. Form liquid . Alternative Name TBC1D4, AS160, NIDDM5, TBC1 domain family member 4, TBC (Tre-2, BUB2, CDC16) domain-containing protein, akt substrate of 160 kDa . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake. . Immunogen AS160 . Specificity Human, Mouse, Rat . Tested Application ELISA, WB . Recommended dilution WB: 1:500 - 1:2000 . IHC use . WB use . RAW 264.7 were subjected to SDS PAGE followed by western blot with PAab09889(AS160 antibody) at dilution of 1:1000 . Protein Information . Gene ID . Uniprot ID O60343 . Calculated MW 50-55 kDa . Research Area Signal Transduction

. Form liquid . Alternative Name asprosin . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Hormone that targets the liver to increase plasma glucose levels. Secreted by white adipose tissue and circulates in the plasma. Acts in response to fasting and promotes blood glucose elevation by binding to the surface of hepatocytes. Promotes hepatocyte glucose release by activating the protein kinase A activity in the liver, resulting in rapid glucose release into the circulation. . Immunogen asprosin . Specificity Human, Mouse . Tested Application ELISA, IHC, WB . Recommended dilution WB: 1:500-1:2000; IHC: 1:200-1:500 . IHC use Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab09797(asprosin Antibody) at dilution of 1:400 . WB use . recombinant proteins were subjected to SDS PAGE followed by western blot with PAab09797(asprosin Antibody) at dilution of 1:1000 . Protein Information . Gene ID . Uniprot ID P35555 . Calculated MW 20 kDa . Research Area

. Form liquid . Alternative Name ATP2B, DAR, DD, SERCA2 . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. . Immunogen ATP2A2 . Specificity Human, Mouse, Rat . Tested Application ELISA, WB, IHC, IF . Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100 . IHC use Immunohistochemistry of paraffin-embedded mouse brain using PAab09918(ATP2A2 antibody) at dilution of 1:100 . WB use . MCF7 cells were subjected to SDS PAGE followed by western blot with PAab09918(ATP2A2 Antibody) at dilution of 1:1000 . Protein Information . Gene ID 488 . Uniprot ID P16615 . Calculated MW 110 kDa . Research Area

. Form liquid . Alternative Name ATP5H, ATP5JD, ATPase subunit d, ATPQ . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Mitochondrial membrane ATP synthase(F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1)-containing the extramembraneous catalytic core, and F(0)-containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. . Immunogen ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d Specificity Human, Mouse . Tested Application ELISA, WB, IHC . Recommended dilution WB: 1:500-1:2000; IHC: 1:50-1:500 . IHC use Immunohistochemistry of paraffin-embedded human kidney using PAab10033(ATP5H antibody) at dilution of 1:100 . WB use . A549 cells were subjected to SDS PAGE followed by western blot with PAab10033(ATP5H antibody) at dilution of 1:1000 . Protein Information . Gene ID 10476 . Uniprot ID O75947 . Calculated MW 19-22 kDa . Research Area Signal Transduction, Metabolism

. Form liquid . Alternative Name PWD, WC1, WD, WND . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). . Immunogen ATP7B . Specificity Human . Tested Application IHC . Recommended dilution IHC: 1:50 - 1:200 . IHC use Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab09904( ATP7B antibody) at dilution of 1:100 . WB use . Protein Information . Gene ID 540 . Uniprot ID P35670 . Calculated MW 30 kDa . Research Area Metabolism, Signal Transduction

. Form liquid . Alternative Name ATPMB, ATPSB, HEL-S-271 . Purification protein A+G purified . Purity 95% as determined by SDS-PAGE . Host Mouse . Isotype IgG1 . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Immunogen ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide Specificity Human, Mouse, Rat . Tested Application ELISA, WB, IHC . Recommended dilution WB: 1:5000 - 1:30000; IHC: 1:200 - 1:1000 . IHC use Immunohistochemistry of paraffin-embedded rat heart using PAab09949(ATPB antibody) at dilution of 1:500 . WB use . Hela cells were subjected to SDS PAGE followed by western blot with PAab09949(ATPB antibody) at dilution of 1:10000 . Protein Information . Gene ID 506 . Uniprot ID P06576 . Calculated MW 56 kDa . Research Area Metabolism

. Form liquid . Alternative Name AIK, ARK 1, ARK1, AURA, AURKA, Aurora A, aurora kinase A, Aurora related kinase 1, Aurora/IPL1 related kinase 1, AURORA2, Breast tumor amplified kinase, BTAK, hARK1, STK15, STK6, STK7 . Purification Immunogen affinity purified . Purity 95% as determined by SDS-PAGE . Host Rabbit . Isotype IgG . Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.) . Background/ FUNCTION . Immunogen aurora kinase A . Specificity Human . Tested Application ELISA, WB, IHC . Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 . IHC use Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using PAab10043(AURKA Antibody) at dilution of 1:200 . WB use . Hela cells were subjected to SDS PAGE followed by western blot with PAab10043(AURKA Antibody) at dilution of 1:1000 . Protein Information . Gene ID 6790 . Uniprot ID O14965 . Calculated MW 46 kDa . Research Area Cancer, Cell Division and Proliferation, Metabolism