Packing 100ul

SKU: PAab09852 Categories: , ,


. Form liquid
. Alternative Name AMOT, angiomotin, KIAA1071
. Purification Immunogen affinity purified
. Purity 95% as determined by SDS-PAGE
. Host Rabbit
. Isotype IgG
. Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
. Background/ FUNCTION
. Angiomotin belongs to the motin family of angiostatin binding protein. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Most abundant expression was found in placenta and skeletal muscle. AMOT has two isoforms with MW 130 kDa (p130) and 80 kDa (p80). The p130 isoform can interact with F-actin.This antibody recognizes both p130 and p80.
. Immunogen angiomotin
. Specificity Human
. Tested Application ELISA, WB, IHC, IF, IP
. Recommended dilution WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200
. IHC use Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using PAab09852(AMOT Antibody) at dilution of 1:200
. WB use
. HEK293 cells were subjected to SDS PAGE followed by western blot with PAab09852(AMOT Antibody) at dilution of 1:1000
. Protein Information
. Gene ID 154796
. Uniprot ID Q4VCS5
. Calculated MW 62 kDa
. Research Area Cardiovascular, Developmental biology

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