Description
β2-Glyco-Check is a solid phase enzyme immunoassay employing native β2-glycoproteinI highly purified from human plasma for the combined quantitative detection of IgA, IgG and IgM antibodies against β2-glycoprotein I in human serum. Anti-β2-glycoprotein I antibodies recognize specific epitopes on human β2-glycoprotein I which are expressed only when β2-glycoprotein I interacts with lipid membranes or when absorbed to other surfaces (e.g. microtiter plate). The assay is an aid in the diagnosis and risk of primary and secondary antiphospholipid syndrome (APS).